What medications are the most commonly used for treatment?
Currently, 5 drugs are specifically approved by the US Food and Drug Administration specifically for the treatment of PAH. They include (alphabetically): ambrisentan, bosentan, epoprostenol sodium, iloprost, sildenafil and treprostinil. Additionally, calcium channel antagonists may be useful in a small group of patients with PAH. Diuretics, digoxin and oxygen are also helpful in advanced cases. Most patients are also treated with the anticoagulant, warfarin. Several research protocols exist to assess the efficacy of new agents in the treatment of PAH at a number of PAH specialty centers.
