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What may lead to epTIPS boxes becoming deformed during autoclaving?

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What may lead to epTIPS boxes becoming deformed during autoclaving?

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The geometry of the epBox housing changes when the box(es) is (are) forced into the autoclave and the door of the autoclave can only be closed with a degree of force. Once the autoclave has cooled down, the deformed shape is retained. Stacking of many boxes should also be avoided. What is more, autoclaving temperature should be checked regularly. Experience suggests that autoclaves are frequently operated at excessive temperatures. The permissible temperature quoted by Eppendorf should never be exceeded.

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