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What may contribute to a false negative result (e.g., mother admits to drug use, yet meconium drug test is negative?

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What may contribute to a false negative result (e.g., mother admits to drug use, yet meconium drug test is negative?

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A false negative reading is often due to a problem from meconium sampling. There should always be enough meconium to fill a heaping of the collecting spoon. If there is not enough meconium scooped out, the results may be negative due to insufficient material analyzed. Similarly, a higher positive yield can be achieved by collecting meconium from two diapers. The samples can be mixed into one, and then test samples obtained from this mixture.

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