What may cause autosomal dominant polycystic kidney disease?
ADPKD is most often caused by damaged genes. Genes are little pieces of information which tell your cells how to grow and what to do. Damaged genes may be passed on to you by your parents. Damage to your genes may also occur from taking certain medicines and hormones (special chemicals). Damaged genes may cause decreased blood flow to your kidneys. Decreased blood flow may cause the cysts to form in your kidneys. For a small number of people, the cause of ADPKD may be unknown.