What mab(s) is important to initially monitor infected cells?
In the life cycle of HHV-6 replication, IE antigen appears between 4-8 hours post infection followed by early antigen (P41) which appears between 12-18 hours. After this viral DNA synthesis starts, late proteins, such as gp116/64/54, appear which tells you that virus replication is taking place. Therefore, use IE-2 (HHV-6A specific), P41 and gp116/64/54 to monitor the infection.