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What lifetime should I expect from a Cyano HPLC column?

April 26, 2017column cyano expect hplc lifetime

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What lifetime should I expect from a Cyano HPLC column?

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While Cyano HPLC columns have suffered from a reputation of not lasting very long, with type B silica (high purity) and proper bonding technologies, a Cyano column that is conditioned and treated properly should last as long as any other column. To lengthen column life avoid using mobile phases with a pH higher than 7.0 with Cyano and Amino columns.