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What kinds of adducts are commonly observed in mass spectrometry?

April 26, 2017adducts Commonly mass spectrometry

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What kinds of adducts are commonly observed in mass spectrometry?

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– By CI with methane, it is common to observe an MH+ ion, but many compounds also exhibit a significant (M-H)+ ion. By CI with methane you will also sometimes observe much smaller (M+C2H5)+ and (M+C3H5)+ adduct ions. For FAB, you usually detect an (MH)+ molecular ion and some fragments. You will also observe fragment and adduct ions from the matrix. At JHU, we normally employ 3-nitrobenzyl-alcohol as the matrix (m-NBA) which forms significant ions at m/z = 136, 154, 289, 307 and 460.