What is wrong with the definition of Normal?
The determination of normal ranges is based upon surveys of people who have been clinically assessed as being “normal”, the assumption being made that such persons are completely “normal” in every respect and therefore every one of their biochemical markers will also be exactly “normal” at all times. If for instance, because of the existence of a disease susceptibility or sub clinical disease, participants in such trials have blood values which lie outside the “normal range”, then since such participants have been declared “normal”, the normal range must be extended to include this data.
