What is the yield of nucleated cells after processing?
The number of total nucleated cells is the most important indicator of a successful transplant. The disadvantage of cord blood is a lower number of cells compared to bone marrow due to the smaller volume. The more cells that are lost during processing, the less chance there is for the transplant to be as successful in larger patients. During processing, 20-60% of total nucleated cells can be lost. The yield, in terms of percentage, is the number of nucleated cells left after processing, divided by the number of cells before processing, and then multiplied by 100. With the superior double processing technique developed by Dr. H. Yang et al, the average yield of total nucleated cells at Progenics is over 97.6%.
