What is the usual final dose of venlafaxine?
While doses up to 375 mg per day are approved by the FDA, some severely depressed patients have been treated with higher doses. Most depressed people respond to doses under 300 mg per day. • How long does it take venlafaxine to relieve depression? While most people taking venlafaxine become aware of some lessening of depression within two to four weeks, there are some who experience relief within the first week and others who only experience relief after a couple of months of therapy. • Are there withdrawal effects if venlafaxine is suddenly discontinued? Because of its very short half-life, venlafaxine should be discontinued gradually over at least 2 weeks. If venlafaxine is suddenly discontinued, a withdrawal syndrome involving fatigue, nausea, dizziness, headache, insomnia, and nervousness may develop. • Is venlafaxine toxic if an overdose is taken? Fourteen overdoses of venlafaxine have been reported. In some cases venlafaxine was taken along with alcohol and/or other medications.
