What is the upper limit of genome size amenable to Optical Mapping?
Prokaryotes and small eukaryotes can be Mapped, with the larger genome projects of 50-100Mb requiring more sample preparation, processing and Mapping time. Bacterial genomes contain a single chromosome and typically range up to about 6Mb in size, contrasted to Yeast and fungal genomes which contain multi-chromosomes and the genomes are much larger.