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What Is The Underlying Genetic Cause Of Congenital Pain Insensitivity?

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What Is The Underlying Genetic Cause Of Congenital Pain Insensitivity?

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F. B. Axelrod et al., Gene Reviews, Univeristy of Washington, Heditary Sensory and Autonomic Neuropathy IV: http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=gene&part=hsan4 K. Huehne et al., Novel missense, insertion and deletion mutations in the neurotrophic tyrosine kinase receptor 1 type gene (NTRK1) associated with congenital insensitivity to pain and anhidrosis, Neuromuscular Disorders 18:159-166 (2008). S. Mardy et al., Congenital Insensitivity to Pain with Anhidrosis: Novel Mutations in the TRKA (NTRK1) Gene Encoding A High-Affinity Receptor for Nerve Growth Factor, American Journal of Human Genetics 64:1570-1579 (1999).

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