What is the Treatment of Well-Differentiated Thyroid Cancer?
The primary therapy for well differentiated thyroid cancer is surgical removal of the tumor, which also allows preliminary staging of the disease. When a skilled thyroid surgeon is available, a bilateral near total removal of the thyroid (thyroidectomy) should be performed for most patients with known papillary or follicular carcinoma. However, there are many patients, previously treated with removal of half of the thyroid gland (hemithyroidectomy) who continue to thrive without disease recurrence. A particular dilemma occurs when the diagnosis of a minimally invasive follicular carcinoma is made after final pathology review, usually days after surgery is completed. Preliminary pathological analysis (frozen section) generally cannot distinguish benign from malignant follicular tumors at the time of surgery. Therefore removal of only half of the thyroid is generally performed. When the final diagnosis is minimally invasive follicular carcinoma options include: additional surgery to remo
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