What is the TRANSIL technology?
The core of the TRANSIL technology are silica beads with specific surface chemistry. The beads are modified such that we can covalently bind proteins or non-covalently bind membranes to their surface. Protein covered beads have very little exposed bead surface which itself has specific properties which prevents unspecific binding of test substances. Membrane beads carry true phospholipid bilayers of natural membrane composition. These membranes are reconstituted in our laboratory from natural materials and mimic precisely true membrane properties such as fluidity and molecular interactions. The key advantage of the TRANSIL technology is that the products are all based on natural materials that are reconstituted in a highly defined way in our laboratories, such that our assays offer unsurpassed reproducibility. At the same time they directly measure the key parameters of interest, since they are based on the natural materials of interest. The beads in one 96-well plate have roughly the