What is the tolerability of advantix in dogs and in pups?
advantix was evaluated in studies on tolerability in domestic animals both in adult dogs and in pups. Adult dogs and pups of over seven weeks of age and younger were treated weekly for four weeks with topical applications of advantix at doses equal to five times that indicated initially. Even after application of such excessive doses, no adverse effects were observed. However, the use of advantix is recommended in animals weighing over 1.5 kg.