What is the significance of ductal carcinoma in-situ (DCIS) in terms of prognosis and treatment?
DCIS is a pre-cancer but its natural history is not well understood. Treatment is aimed at getting rid of all the DCIS, usually by surgery alone. However, in some cases, radiation (radiotherapy) or hormonal therapy will follow surgery in order to help prevent the DCIS from coming back (recurring) or also possibly developing into invasive carcinoma.8. What does it mean if my report mentions special studies such as high molecular weight cytokeratin (HMWCK), CK903, CK5/6, p63, muscle specific actin, smooth muscle myosin heavy chain, calponin, or keratin?These are special tests that the pathologist sometimes uses to help make the diagnosis of ductal carcinoma in-situ. Not all cases need these tests. Whether your report does or does not mention these tests has no bearing on the accuracy of your diagnosis.