What is the side effect of taking Metformin tablets daily?
Common Metformin Side Effects Metformin and metformin ER have been studied thoroughly in clinical trials, with many people having been evaluated. In these studies, side effects occurring in a group of people taking the drug are always documented and compared to side effects that occur in a similar group of people not taking the medicine. Based on these studies, the most common metformin side effects include: •Diarrhea — occurring in up to 53.2 percent of people •Nausea or vomiting — in up to 25.5 percent •Gas — in up to 12.1 percent •Weakness — in up to 9.2 percent •Indigestion — in up to 7.1 percent •Abdominal discomfort (or stomach discomfort) — in up to 6.4 percent •Headache — in up to 5.7 percent. Generally, people have fewer side effects when taking the long-acting form (metformin ER). Common side effects for metformin ER include diarrhea (in up to 9.6 percent of people) and nausea or vomiting (in up to 6.5 percent of people).