What Is the Scientific Evidence for Inositol?
Small double-blind studies have found inositol helpful for depression.23,24 In one such trial, 28 depressed individuals were given a daily dose of 12 g of inositol for 4 weeks.25 By the fourth week, the group receiving inositol showed significant improvement compared to the placebo group. However, a double-blind study of 42 people with severe depression that was not responding to standard antidepressant treatment found no improvement when inositol was added.
