What is the safety profile of Cathflo?
Adverse events seen in the largest clinical trial involving Cathflo included sepsis (0.4%), major hemorrhage (0.4%), gastrointestinal bleeding (0.3%), and venous thrombosis (0.3%).2,3 There were no instances of intracranial hemorrhage (ICH) or embolic events. Cathflo should not be administered to patients with known hypersensitivity to Alteplase or any component of the formulation. It should be used with caution in the presence of known or suspected infections in the catheter. Using Cathflo in patients with infected catheters may release a localized infection into the systemic circulation.
