What is the rule for classifying a synchronous versus a metachronous second primary tumour?
If a new primary cancer is diagnosed within two months, the new cancer is considered synchronous; otherwise it is metachronous (based on criteria used by the SEER Programme of the National Cancer Institute, USA). Metachronous tumours are classified separately from the preceding tumour. General rule No. 5 discusses the rules for classifying simultaneous (synchronous) tumours. 1.
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