What is the role of progestin in hormone therapy?
Clinical studies show that the addition of progestin to an estrogen treatment for at least 12 days per cycle reduces, but does not eliminate, the incidence of enlargement of benign tumors of the uterus (fibroids) and the potential risk of cancer of the uterus in women with an intact uterus. The addition of progestin to an estrogen treatment has not been shown to interfere with the effectiveness of hormone therapy for its approved uses.
