What Is The Role Of Enzymes In Diagnosis?
The idea is that when organs which produce specific enzymes get injured, enzyme activity decreases in the organ and the concentration of these enzymes increase in the plasma. Thus, biochemical investigations are set up to measure increases in plasma of enzyme activity.So when diagnosing certain conditions like myocardial infarction, the enzyme activity in plasma is measured assuming that all enzymes in the human body are synthesized intracellularly.There are significant quantities in plasma once cells of organs are damaged which are measured.Enzyme activity is normally related to the number of cells damaged and thus to the extent of lesion.Correct interpretation of enzyme activity in disease depends on understanding: »factors that affect the rate of enzyme release from cells of origin »the rate at which they are cleared from circulation Thus professionals have come up with typical graphs of increase in activity of enzymes after certain occasions like myocardial infarction.
