What is the risk of serious reactions following IPV?
In very rare circumstances, IPV, like any medicine, can cause serious problems, such as a severe allergic reaction. IPV should not be administered to persons who have experienced a severe allergic reaction after a previous dose of IPV or to streptomycin, polymyxin B, and neomycin. The risk of a polio shot causing serious harm, or death, is extremely small.
