What is the required biosafety level for using recombinant lentiviruses at University of Michigan?
All viruses handled at the University of Michigan need to be registered with UM Institutional Biosafety Committee (IBC). The IBC determines the biosafety level for each virus. In general, most of the recombinant viruses produced in the Vector Core are classified in Biosafety Level II for agents considered of ordinary potential harm. These recombinant viruses include E1, E3-deleted adenovirus and third-generation, self-inactivating (sin) lentivirus. Federal regulations can be found here. Return to top. Return to lentivirus faq.