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What is the relevance of determining EGFR-variant-III status in glioblastomas?

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What is the relevance of determining EGFR-variant-III status in glioblastomas?

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Pelloski CE et al. (2007) Epidermal growth factor receptor variant III status defines clinically distinct subtypes of glioblastoma. J Clin Oncol 25: 2288–2294 Synopsis Background The prognostic value of EGFR-variant-III (EGFRvIII) expression in glioblastomas has not been determined.

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