What is the relationship between arthritis and Pagets disease?
A. Paget’s disease can cause arthritis by changing bones around joints: (1) long bones such as the thigh and leg bones may become bowed and distort the normal alignment and pressures within the adjacent joints; (2) bone with Paget’s disease may become enlarged, causing the joint surfaces to undergo excessive wear and tear. Osteoarthritis is a common cause of pain in Paget’s disease, but the disease itself also causes bone pain. In many patients, the bone pain may be due to a combination of Paget’s disease and osteoarthritis.