What is the recommended length of time a woman should wait after receiving rubella (or MMR) vaccine before becoming pregnant?
Four weeks. In October 2001, ACIP voted to change its recommendation for the waiting interval following the administration of rubella vaccine. The interval was reduced from 3 months to 4 weeks. The waiting period for measles and mumps vaccine was already one month. • If a pregnant woman had a positive rubella titer in the past, and now has a negative rubella titer, she would not need another MMR vaccination. Doesn’t the negative rubella titer mean her immunity has waned and she needs a booster dose? Rubella antibody levels may decline with time, and may even fall below the level of detection of standard screening tests. However, data from surveillance of rubella and congenital rubella syndrome suggest that waning immunity with increased susceptibility to rubella disease does not occur (MMWR 1998;47[RR-8]:14). Studies of persons who have “lost” detectable rubella antibody indicate that almost all had antibody detectable by more sensitive tests, or demonstrated a booster-type response (a
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