What is the recommended HRT dosage for POF? Is it better to use HRT instead of BCP?
First of all, Birth Control Pills are fine to take. It is generally believed that women with POF do better with more than postmenopausal doses of estrogen. Premarin 1.25mg is appropriate if it helps your symptoms. If you feel like you are taking too much estrogen (and this is already less than what’s in the birth control pill), then 0.625 or a patch doses of 50 micrograms can be given. 100 microgram patches can also be used when needed. There’s no “correct” dose, use what controls symptoms and protect bone density. The minimum dose is 0.625mg Premarin or 50 microgram patches. Provera can be given in the usual fashion, 5-10mg a day for at least 12 days each month. Oral micronized progesterone is an alternative. The dosing of this at higher estrogen doses beyond 0.625mg Premarin or 50 microgram patch doses has not been well worked out. You would need some fine tuning to figure that out.
