What is the reason for a negative mD result, although the clinical symptoms point to a periodontitis?
This may be due to the fact that the patient is for example PST-positive, i.e. he reacts more strongly to the periodontal marker microorganisms below the detection limit. It may also be due to an inadequate supragingival cleaning or the fact that other rare microorganisms are responsible for the periodontitis (e.g. viruses such as herpes), he may be immunodeficient e.g. in the case of diabetics, HIV or leukaemia patients or the patient has been treated with antibiotics in the recent weeks for an infection. Possible sources of error when taking samples: – incubation period too short (ideally 10-20 sec.
