What is the rationale for the Missouri S&T cDNA Resource Center?
Biological research often involves the reconstruction of signaling pathways. The basic tools required in this work are the clones of the relevant interacting proteins. We found that we were spending inordinate amounts of time obtaining, verifying and modifying these clones. Accordingly, we felt that research would be accelerated and a great deal of duplicate effort eliminated if there was a service that provided rapid access to high quality sequence-verified clones. We offer human clones because of their obvious inherent interest. We remove the untranslated regions because their presence often increases variability in expression. We utilize a standard vector to simplify handling procedures.
