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What is the Quad Screen?

down syndrome open neural tube defects (ontds) Quad quad screen screen trisomy 18
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What is the Quad Screen?

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The Quad Screen is a test of the mother’s blood in the second trimester of pregnancy (15 to 21 weeks). The test looks for an increased risk of Down syndrome, Trisomy 18, and open neural tube defects. It measures the concentrations of the following four markers: • alpha-fetoprotein (AFP) • human chorionic gonadotrophin (hCG) • unconjugated estriol (uE3) • Inhibin-A (Inh-A) The Quad Screen has a detection rate of 84% with a false-positive rate of 5%.

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