What is the purpose of the plastic membrane in the LeucoSep and Lymphoprep® tubes?
These plastic porous membranes are called frits and help in two ways for rate zonal and barrier techniques. The first way they help is making the addition of your sample to the density gradient medium much faster; you don t have to slowly add the sample to avoid mixing it with the density gradient medium. The second way is generally improved yields and purities, as the discontinuous gradient between your sample and the medium is stringently maintained up until the centrifuge has started.
