What is the purpose of the In-111 ZEVALIN scan?
The In-111 ZEVALIN gamma camera scan is used to confirm that the expected biodistribution of the radiolabeled antibody In-111 ZEVALIN is present prior to administration of the therapeutic dose of Y-90 ZEVALIN. Whole-body gamma camera images must confirm that the expected biodistribution of In-111 ZEVALIN is present in order to proceed with administering the ZEVALIN therapeutic regimen. Please see full Prescribing Information for ZEVALIN for further details on the expected biodistribution of In-111 ZEVALIN. Do not administer Y-90 ZEVALIN to patients with altered biodistribution. Biodistribution may be re-assessed after correction of underlying factors.1 Because Y-90 ZEVALIN is not a gamma emitter, it cannot be used for imaging. Note that the In-111 ZEVALIN scan is not used to determine the therapeutic dose of Y-90 ZEVALIN.
