What is the purpose of IV Immunoglobulin therapy for TM? (What is it and how does it work)?
Intravenous immunoglobulin (IVIg) refers to the infusion of human immunoglobulins or antibodies in an attempt to modulate the immune system. Blood is obtained from pools of 3,000 to 10,000 donors and the immunoglobulins are extracted from the plasma fraction of that blood. The immunoglobulin preparation is then treated in several ways to kill or inactivate viruses, including human immunodeficiency virus (HIV) and the various hepatitis viral agents. HIV has never been transmitted through IVIg. There are cases of hepatitis transmission via IVIg in the past, but newer methods of treatment of the IVIg have proven safe in prevention of the transmission of hepatitis virus. IVIg is currently used to treat many autoimmune diseases. The exact manner in which it works is unclear. However, each batch is a mixture of human antibodies directed against a wide spectrum of human and foreign proteins. Many of these antibodies actually bind to the antibodies in the patient who receives them as a treatme