What is the principle of MATra?
Magnet Assisted Transfection (MATra) is a new, easy-to-handle and highly efficient method to transfect cells in culture. Using this new technique nucleic acids, such as plasmid DNA, oligonucleotides or siRNA, are in a first step associated with magnetic nanoparticles. Exploiting magnetic force, the full nucleic acid dose is then rapidly drawn towards and delivered into the target cells leading to efficient transfection. For MATra, cells must adhere to the bottom of the culture vessels which makes special precautions necessary for suspension cells.
