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What is the physiological significance of hemoglobin oxygen dissociation curve as S-shaped?

April 26, 2017Chemistry curve dissociation Hemoglobin Mathematics oxygen physiological significance

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What is the physiological significance of hemoglobin oxygen dissociation curve as S-shaped?

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The sigmoid shape of Hb oxygen dissociation curve describe the relationship between the partial pressure of oxygen and the oxygen concentration in the blood. The curve is shifted to the left showing increased oxygen affinity by a fall of Pco2, a rise in pH and temperature. The shifted to right implying increased blood CO2 level, that means the decreasing of oxygen.