What is the Physiological Process During a Cholinergic Urticaria Reaction?
At this point in time, researchers are aware of the mast cell involvement, involvement of acetylcholine, the hypothalamus, and histamine during a reaction of cholinergic urticaria. So it may help to first understand these individual components, and then we can see how they interact during a reaction. This article will contain basic information about these processes. The physiological process of cholinergic urticaria seems to be this (simplified format): Hypothalamus–>Acetylcholine–>Mast Cells–>Histamine Release–>Hives.
