What is the Pathwork® Tissue of Origin Laboratory Developed Test (LDT)?
The Pathwork® Tissue of Origin LDT is an innovation in molecular diagnostics—a gene expression–based test that uses a tumor’s own genomic information to reliably pinpoint its origin. The test provides objective data previously unavailable to physicians for tissue of origin identification. The Tissue of Origin Test, developed by Pathwork Diagnostics, measures the expression pattern, comprising more than 1500 genes, in a tumor to compare it to expression patterns of a panel of 15 known tumor types, representing 58 morphologies and covering 90% of all solid tumors. It produces a report with an objective score for each potential tissue. The test uses a proprietary Pathchip® microarray and runs on the proven Affymetrix GeneChip® System.
