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What is the particle to infectivity ratio of the viruses?

April 26, 2017infectivity particle ratio viruses

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What is the particle to infectivity ratio of the viruses?

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Particle to infectivity ratio is the ratio of total virus particles to the number of infectious virus particles. The ratio for wild type viruses is usually around 10:1 and the ratio for replication-deficient viruses is usually between 20:1 and 50:1. We perform plaque assays on our viruses to obtain a measure of infectious viral titre but the ratio is different for each different batch.