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What is the nature of the link between diet drugs and PPH / PAH?

diet drugs link Nature PAH pph
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What is the nature of the link between diet drugs and PPH / PAH?

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A. Recent evidence has come to light which suggests a link between certain appetite suppressants and PPH / PAH. These include fenfluramine (marketed as Pondimin), dexfenfluramine (marketed as Redux), and the fenfluramine-phentermine drug combination, known as Fen-Phen. Studies estimate that treatment with these drugs increases a patient’s risk of developing PPH / PAH from about 1 to 28 cases per million person-years (one person-year represents a patient treated for one year). Learn more about diet drugs and PPH / PAH.

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