What is the motivation to continue research ad infinitum?
It’s the thrill of the surprise when we discover something new, something that has bewildered us for days, months or years and now suddenly makes sense. That thrill is something we get to experience only rarely, but it’s what drives us onwards. You were the co-discoverer of mitochondrial DNA. You discovered that the power generators inside our cells have their own genotype. How do you discover something like that? Mostly by trying to refute a hypothesis. In order to explain the biogenesis of mitochondria in living cells, we postulated the hypothesis that mitochondria contain their own genes. Then we tried to knock down this hypothetical snowman in our experiments. But it stood up against all the snowballs we threw at it, and we found that mitochondria really do contain small amounts of DNA genetic material. If science is a game, is it a team game or something you play alone? Most scientists tend by their very nature to be introverted. This intellectual solitude is probably essential fo
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