What is the most important information I should know about urokinase (Abbokinase, Kinlytic)?
You should not use this medication if you are allergic to urokinase, or if you have: • internal bleeding; • a brain tumor; • a brain aneurysm (dilated blood vessel); • a bleeding or blood clotting disorder (such as hemophilia); • a condition called arterial hypertension; • if you have had a recent medical emergency requiring CPR (cardiopulmonary resuscitation); • if you have had a stroke, brain surgery, or spinal surgery within in the past 2 months. If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before you receive urokinase, tell your doctor if you have: • a history of stroke; • severe liver or kidney disease; • eye problems caused by diabetes; • an infection of the lining of your heart (also called bacterial endocarditis); • a blood clot of your heart; • a recent history of stomach or intestinal bleeding; • if you are pregnant or have had a baby within the past 10 days; or • if you have had surgery or an organ transplant