What is the most important information I should know about Promethazine hydrochloride?
Promethazine should not be used in children younger than 2 years old. Serious and sometimes fatal side effects (difficult or slowed breathing, drowsiness leading to coma) have occurred when promethazine has been used in children in this age group. Promethazine should be used with extreme caution in children 2 years of age and older. The lowest effective dose should be used in this age group. Do not drive or perform other possibly unsafe tasks until you know how you react to promethazine; this drug may cause dizziness, drowsiness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Do not drink alcohol or use medicines that may cause drowsiness (such as sleep aids and muscle relaxers) while you are using promethazine; it may add to their effects. Neuroleptic malignant syndrome (NMS) is a possibly fatal syndrome that can be caused by promethazine. Symptoms may include fever; stiff muscles; confusion; abnormal thinking; fast or irregular heartbe
