What is the most important information I should know about Kinlytic (urokinase)?
You should not use this medication if you are allergic to urokinase, or if you have: • internal bleeding; • a brain tumor; • a brain aneurysm (dilated blood vessel); • a bleeding or blood clotting disorder (such as hemophilia); • a condition called arterial hypertension; • if you have had a recent medical emergency requiring CPR (cardiopulmonary resuscitation); • if you have had a stroke, brain surgery, or spinal surgery within in the past 2 months. If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before you receive urokinase, tell your doctor if you have: • a history of stroke; • severe liver or kidney disease; • eye problems caused by diabetes; • an infection of the lining of your heart (also called bacterial endocarditis); • a blood clot of your heart; • a recent history of stomach or intestinal bleeding; • if you are pregnant or have had a baby within the past 10 days; or • if you have had surgery or an organ transplant
You should not use this medication if you are allergic to urokinase, or if you have internal bleeding, a brain tumor or aneurysm, hemophilia or other bleeding disorder, arterial hypertension, or if you have had a recent stroke, surgery, organ transplant, or medical emergency . Before you receive urokinase, tell your doctor if you have liver or kidney disease, diabetes, heart problems, if you are pregnant or recently gave birth, a history of stroke or stomach bleeding.Tell your caregivers at once if you have a serious side effect such as easy bruising or bleeding, blood in your stools, coughing up blood, chest pain, sudden problems with vision or speech, swelling, discoloration of your fingers or toes, severe stomach pain, weak or shallow breathing, fever, chills, or flu symptoms. Before you receive urokinase, tell your doctor if you are using a blood thinner such as warfarin (Coumadin), aspirin or an NSAID (non-steroidal anti-inflammatory drug) such as ibuprofen (Motrin, Advil), naprox
