What is the Most Appropriate Anti-microbial Treatment for Tuberculous Meningitis?
The WHO Pocketbook of Hospital Care for Children recommends as the optimal treatment regimen, where there is no drug resistance: • isoniazid (10 mg kg–1) for 6–9 months; • rifampicin (15–20 mg kg–1) for 6–9 months; and • pyrazinamide (35 mg kg–1) for the first 2 months. It does state however to follow national tuberculosis programme guidelines (p. 151).
