what is the minimum gluten dietary content necessary for the optimal accuracy of serological tests and intestinal biopsy for the diagnosis of coeliac disease?
– There is no robust evidence on how much gluten people should include in their diet when undergoing testing for coeliac disease. Different definitions are used, based on a single study and expert opinion, and this can lead to confusion among patients and clinicians. Although it is evident that a gluten-containing diet for a sustained period is necessary to ensure that serological test results are as accurate as possible and that intestinal biopsy results are as clear as possible, the amount of gluten and the period of intake needed are unknown. Research is needed on how serological tests and intestinal biopsy accuracies are associated with gluten intake in order to define the minimum level of gluten and period of intake for adults and children with suspected coeliac disease. How many people with undiagnosed coeliac disease are misdiagnosed as having other conditions, and what are the clinical and cost implications of this? – People with coeliac disease often have significant health pr
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