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What is the mechanism of cell membrane binding to Wheat Germ Agglutinin and Polylysine SPA beads?

April 26, 2017agglutinin beads Binding cell membrane Germ mechanism polylysine spa wheat

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What is the mechanism of cell membrane binding to Wheat Germ Agglutinin and Polylysine SPA beads?

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A. Cell membranes couple to the wheat germ agglutinin (WGA) coated SPA beads through interactions between WGA and N-acetylglucosamine residues that are present in glycosylated cell surface proteins. In the case of polylysine coated SPA beads, salt-bridges form between the positively charged polylysine sites on the bead and the negatively charged lipids that comprise the cellular membrane.