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What is the meaning of uptake I, uptake II & uptake III?

ii III uptake
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What is the meaning of uptake I, uptake II & uptake III?

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After stimulating the adrenergic receptors, the body tries to get rid of the released norepinephrine or epinephrine by either: 1) Uptake into the nerve ending (uptake I) to be followed by either metabolism or uptake into the storage vesicles for further use (uptake III) 2) Uptake into the target organs (uptake II) which is followed by metabolism.

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