What Is the Meaning of Quantitative CBF?
A. Gregory Sorensen, M.D., Member, Editorial Board Proponents of MR imaging, CT with iodine, xenon CT, positron emission tomography (PET), sonography, and soon-to-be-available optical modalities often claim that these techniques quantitate CBF. Vendors provide software and hardware to create images that they claim represent CBF, and increasingly, these vendors attach scale bars with numbers on them. In particular, there seems to be something magical when the vendor can promise “absolute CBF” in mL/100 g/min. Often, articles, such as the one authored by Kikuchi et al in this issue of the AJNR (page 248), indicate that the method being described has this ability to provide absolute quantitation. How might neuroradiologists view such a claim? Certainly, true quantitation of CBF might well be of tremendous clinical value. Animal and some human data seem to indicate that in the case of acute cerebral ischemia, the level and duration of the ischemia are critical in determining tissue outcome
Related Questions
- PREFERRED ORIENTATION OF MINERAL GRAINS IN SAMPLE MOUNTS FOR QUANTITATIVE XRD MEASUREMENTS: HOW RANDOM ARE POWDER SAMPLES?
- Has Xenon/CT been validated against other proven quantitative CBF measurements in both normal and diseased states?
- Is there a standard unit of measure for HCV-RNA quantitative assays?
