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What is the maximum changes I can make to a method to increase the chances of meeting system suitability in HPLC?

changes hplc increase maximum meeting method suitability system
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What is the maximum changes I can make to a method to increase the chances of meeting system suitability in HPLC?

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This is a question that is always asked and the following are only guidelines. For exact details, consult the FDA or the USP.

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